| Gadolinium MRI and risk factors for the
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| | in the United States: Magnevist,
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| debilitating disease nephrogenic systemic
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| | MultiHance, Omniscan, OptiMARK, and
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| fibrosis (NSF) are currently being
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| | ProHance.
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| investigated by the Food and Drug
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| | Evidence has been increasing regarding
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| Administration (FDA). An MRI with
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| | the risk of nephrogenic systemic fibrosis
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| gadolinium is a type of MRI that uses a
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| | (NSF) in patients with severe kidney
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| contrast agent with special magnetic
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| | problems who receive gadolinium during an
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| properties to help increase the
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| | MRI procedure. Nephrogenic systemic
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| visibility of organs and tissues. Since
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| | fibrosis appears to occur in patients
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| its approval in 1988, MRI with gadolinium
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| | with kidney failure. Patients with kidney
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| has been administered to millions of
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| | disease or on kidney dialysis are at
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| patients.
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| | increased risk because gadolinium is
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| Magnetic resonance imaging (MRI) is a
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| | primarily eliminated by the body through
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| diagnostic study that has been used since
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| | the kidneys.
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| the 1980's. An MRI uses strong magnets
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| | Recent studies have shown an association
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| and radio waves to create computer
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| | between NSF and patients with kidney
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| generated three-dimensional images of the
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| | disease that have a gadolinium MRI.
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| body. When an MRI study is performed,
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| | Unfortunately, there has been little
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| radio waves are pulsed through the
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| | research or clinical trials that have
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| patient's body causing movement in
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| | studied patients with kidney problems and
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| hydrogen atoms in the body's cells.
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| | gadolinium contrast agents. NSF causes
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| Different parts of the body react to the
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| | fibrosis of the skin and connective
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| radio waves with predictable patterns.
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| | tissues throughout the body. The
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| These patterns are displayed as
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| | patient's skin thickens leading to a loss
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| three-dimensional pictures on a computer
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| | of mobility and in some cases causing
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| screen.
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| | death. There is no known treatment or
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| A gadolinium MRI is a special type of
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| | cure for NSF. NSF has only been reported
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| study where the patient is injected with
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| | in patients with severe renal dysfunction
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| gadolinium. For MRI studies using
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| | (kidney disease).
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| gadolinium the procedure usually involves
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| | The Food and Drug Administration (FDA)
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| two MRIs. The first MRI is administered
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| | has requested that the different
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| to get a baseline study. The second study
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| | manufacturers of gadolinium MRI contrast
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| involves injecting the patient with
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| | agent (GBCA) revise their product labels
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| gadolinium and then taking a second MRI.
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| | to include a new warning that describes
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| Gadolinium is a naturally occurring
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| | the increased risk of developing
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| metallic element that has special
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| | nephrogenic systemic fibrosis (NSF). The
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| magnetic properties. Gadolinium gives the
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| | FDA is continuing to review gadolinium
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| treating physician and radiologist a more
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| | for MRI as more studies and reviews
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| detailed picture of the patient's
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| | become available regarding the link
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| internal organs, tissues, bones and
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| | between gadolinium and NSF.
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| vessels. MRI with gadolinium is used
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| | Steve Fields
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| because it provides additional diagnostic
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| | To learn more about Gadolinium MRI please
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| information compared to an MRI without
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| | visit our website.
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| contrast. The Gadolinium for MRI agent is
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| | Our team of gadolinium lawyers represents
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| also referred to as gadolinium-based
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| | clients in Minnesota, Wisconsin, Iowa,
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| contrast agents (GBCA). Five GBCAs are
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| | Arizona, North Dakota, South Dakota and
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| approved for magnetic resonance imaging
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| | throughout the United States.
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